A Device for In Vitro Irradiation with .ALPHA.-Particles Using an .ALPHA.-Emitting Radioactive Source.

Exposure of school children to alpha particles

Background: A substantial part of the public’s natural radiation dose is due to the inhalation of radon gas. Most of the exposure occurs indoors where the airborne concentration of radon and its decay products is usually higher than outdoors. Materials and Methods: Radon activity concentration has been measured twice in 50 classrooms in 5 levels (10 each) during summer and winter using solid-st...

Therapy of Ovarian Carcinoma by Targeted Delivery of Alpha-Particles Using Immunoliposomes Capable of Retaining Alpha-Emitting Daughters

Design criteria and performance parameters of an alpha irradiation device for cell studies

An a irradiation device is described that utilises a commercially available disc-shaped americium-241 source of 8 cm diameter. The a particles traverse a moving collimator and the source is rotated to reduce the influence of source inhomogeneities. Source, collimator and a shutter disc are mounted in a container which is flushed with helium to reduce energy losses of the a particles before reac...

Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells.

Ever since x-rays were shown to induce mutation in Drosophila more than 70 years ago, prevailing dogma considered the genotoxic effects of ionizing radiation, such as mutations and carcinogenesis, as being due mostly to direct damage to the nucleus. Although there was indication that alpha particle traversal through cellular cytoplasm was innocuous, the full impact remained unknown. The availab...

Design and calibration of a passive detector for separating neutron, proton and alpha particles in mixed radiation fields

In this study, calibration process was carried out for deigned new CR-39 nuclear track detector for protons, neutrons and alpha particles separately under the same etching condition. In order to aim this purpose, americium-beryllium standard source (241Am-Be) and Plexiglas phantom for neutron irradiation, brass collimators and americium standard source (241Am) for alpha irradiation and the acce...